22 articles - From Friday Oct 07 2022 to Friday Oct 14 2022
Guidelines, position statements, white papers, technical reviews, consensus statements, etc…
| Kidney Int |
Diabetes management in chronic kidney disease: a consensus report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO). Consensus statements provide specific guidance on use of renin-angiotensin system inhibitors, metformin, sodium-glucose cotransporter-2 inhibitors, glucagon-like peptide 1 receptor agonists, and a nonsteroidal mineralocorticoid receptor antagonist. These areas of consensus provide clear direction for implementation of care to improve clinical outcomes of people with diabetes and CKD. |
| Nephrol Dial Transplant |
meta-analyses and systematic reviews
RCT, clinical trials, retrospective studies, etc…
| Am J Kidney Dis |
Cardiorenal Outcomes Among Patients With Atrial Fibrillation Treated With Oral Anticoagulants. Among patients with non-valvular AF treated in routine clinical practice, compared with VKA, DOAC use was associated with a lower risk of CKD progression, AKI, and major bleeding, but a similar risk of the composite of stroke/systemic embolism and death. |
Focal Segmental Glomerulosclerosis Complicating Therapy With Inotersen, an Antisense Oligonucleotide Inhibitor: A Case Report. This case adds to spectrum of renal disease associated with inotersen and indicates that discontinuation of the drug alone may result in resolution of renal complications without additional immunosuppression. Monitoring of renal function is essential in patients with ATTRv receiving inotersen, particularly if there is evidence of existing renal amyloid. |
Improving a Rare Metabolic Disorder Through Kidney Transplantation: A Case Report of a Patient With Lysinuric Protein Intolerance. However data on kidney transplantation in LPI patients is limited and up till now no data on clinical and biochemical improvement after kidney transplantation has been reported. In this case report we describe a rare case of kidney transplantation in a LPI patient with significant improvement in protein tolerance, plasma and urine levels of ornithine, lysine and arginine and on LPI symptoms. |
| Clin J Am Soc Nephrol |
Kidney Protective Effects of SGLT2 Inhibitors. Additionally, these drugs stimulate phosphate and magnesium reabsorption and increase uric acid excretion. Familiarity with kidney specific mechanisms of action, potential changes in kidney function, and/or alterations in electrolytes and volume status which are induced by these widely prescribed drugs will facilitate usage in patients for whom they are indicated. |
| Nephrol Dial Transplant |
Total cortical interstitial inflammation predicts chronic kidney disease progression in patients with lupus nephritis. In contrast to the current NIH interstitial inflammation classification, accounting for interstitial inflammation in the entire cortical parenchyma allows to identify patients at risk for CKD progression in LN. |
Trimethoprim-sulfamethoxazole and the risk of a hospital encounter with hyperkalemia: a matched population-based cohort study. The 14-day risk of a hospital encounter with hyperkalemia was higher in patients newly treated with TMP-SMX vs amoxicillin, and the risk was highest in patients with a low eGFR. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Am J Kidney Dis |
Peritoneal Dialysis Prescription and Adequacy in Clinical Practice: Core Curriculum 2023. A more patient-centered approach emphasizes the importance of individualized treatment, particularly when considering incremental PD and other prescriptions that align with lifestyle preferences. In shifting the focus from small solute clearance targets to patient needs and clinical goals, PD remains an attractive, patient-centered form of kidney replacement therapy. |
| J Am Soc Nephrol |
| Kidney Int |
Blood pressure effects of sodium transport along the distal nephron. However, what also has become clear is that aldosterone itself only stimulates a portion of the mineralocorticoid receptors along this segment, with the others being activated by glucocorticoid hormones instead. These recent insights provide an increasingly clear picture of how this short nephron segment contributes to blood pressure homeostasis and have important implications for hypertension prevention and treatment. |
| Nat Rev Nephrol |
Cisplatin nephrotoxicity: new insights and therapeutic implications. However, the effects of renoprotective strategies on the efficacy of cisplatin chemotherapy needs to be thoroughly evaluated. Further research using tumour-bearing animals, multi-omics and genome-wide association studies will enable a comprehensive understanding of the complex cellular and molecular mechanisms of cisplatin nephrotoxicity and potentially lead to the identification of specific targets to protect the kidney without compromising the chemotherapeutic efficacy of cisplatin. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Clin J Am Soc Nephrol |
| J Am Soc Nephrol |
| Kidney Int |
| Nephrol Dial Transplant |
Letters to the editors and authors’ replies
| Am J Kidney Dis |
| J Am Soc Nephrol |